Medical Discovery News

Space Hibernation for Real

Medical Discovery News Season 18 Episode 885

Space Hibernation for Real

 Welcome to Medical Discovery News.  I’m Dr David Niesel 

 And I’m Dr. Norbert Herzog 

If you saw the movie, Two thousand one, a space odyssey, you’d recognize these famous lines: “Open the pod bay door HAL” and “I’m sorry Dave, I can’t do that”. 

 Yep, the AI, Hal, goes rogue and kills three astronauts in hibernation on the way to Saturn. We hope rogue AIs remain purely sci-fi, but hibernating astronauts are looking pretty real. 

 Hibernation experiments involve using directed ultrasound on animal brains.  They target a mouse’s hypothalamus which is responsible for sleep and the regulation of body temperature.  The animal then enters a hibernation-like state.  

 The soundwaves are able to decrease body temperature by six point two five degrees Fahrenheit and reduce the animal’s heart rate and oxygen consumption.  We see this naturally happening in bears when they hibernate. 

 When the ultrasound was turned off, the mice's brains quickly returned to a normal state.  A variety of animals such as insects, amphibians, fish, and mammals can “naturally” enter hibernation.  

 We don’t understand all the mechanisms involved. They’re all able to significantly reduce their metabolic state so that their heart rate drops to a few beats a minute and breathe as little as once every ten minutes or so.  

The ultrasound experiments mimic these natural changes, but we don’t know how close it really is. Soon, human clinical trials may start. Hibernation makes long-duration space travel possible and gives doctors more time to treat critically ill patients.  

 We are Drs. David Niesel and Norbert Herzog, at UTMB and Quinnipiac University, where biomedical discoveries shape the future of medicine.   For much more and our disclaimer go to medicaldiscoverynews.com or subscribe to our podcast. Sign up for expanded print episodes at www.illuminascicom.com

 

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